Research

March 19, 2019

Genzyme, a Sanofi company, and Cystic Fibrosis Foundation Therapeutics Inc., the nonprofit affiliate of the Cystic Fibrosis Foundation, today announced a research agreement to support the discovery of new drugs to treat people with the most common mutation found in patients with CF, Delta F508. People...

New Clues for Improving Antibiotics for Tolerant Bacteria

by BEF

CF News, Research

March 19, 2019

Source: Scientific American The superbug MRSA (methicillin-resistant Staphylococcus aureus) has provoked fear in doctors and patients alike because it is endowed with genetic characteristics that make it impervious to many antibiotics, and it can be deadly to boot. Less well known, however, is another class of...

Agile Sciences Gets NIH Grant to Study Treatment for Lung Infections

by BEF

CF News, Research

March 19, 2019

The National Institutes of Health (NIH) has awarded Agile Sciences a Phase I STTR Grant to evaluate the efficacy of Agile Sciences’ proprietary Agilyte™ anti-biofilm molecules for treating lung infections of cystic fibrosis patients. The molecules will be tested in a new model of chronic...

Most Parents Unaware of Medical Research Opportunities for Their Kids

by BEF

CF Community, CF News, Research

March 19, 2019

Note: For information about clinical trials related to cystic fibrosis research, please visit our Research page. Eighty-four percent of parents say they don't know about opportunities for their children to participate in medical research; only 5 percent of children have participated in medical research across the...

Changes in Lung Stem Cells May Contribute to CF Progression

by BEF

CF News, Research

March 19, 2019

Researchers at the University of Iowa's Roy J. and Lucille A. Carver College of Medicine have discovered that in cystic fibrosis (CF) patients, the airway glands are depleted of a specific population of airway stem cells that participate in airway repair following injury. Their results are...

Battle of the Bugs: Pseudomonas Breaches Cell Wall of Rival Bacteria Without Hurting Itself

by BEF

CF News, Research

March 19, 2019

Microbiologists have uncovered a sneaky trick by the bacterium Pseudomonas aeruginosa to oust rivals. It deploys a toxin delivery machine to breach cell walls of competitors without hurting itself. Its means of attack helps it survive in the outside environment and may even help it...

New Invasive Diagnostic Procedure Seems to Be No Advantage Over Current Standard Procedure

by BEF

CF News, Research

March 19, 2019

By Anne Hudsmith, Medical News Today A comparative study published in July 13 issue of JAMA noticed treatment based on a new invasive diagnostic procedure for treating cystic fibrosis in infants that involves obtaining and culturing fluid samples from the lungs, when compared with standard diagnostic...

Bacteria Use Batman-Like Grappling Hooks to ‘Slingshot’ on Surfaces, Researchers Find

by BEF

CF News, Research

March 19, 2019

Bacteria use various appendages to move across surfaces prior to forming multicellular bacterial biofilms. Some species display a particularly jerky form of movement known as "twitching" motility, which is made possible by hairlike structures on their surface called type IV pili, or TFP. "TFP act like...

Researchers Discover New Airway Stem Cell

by BEF

CF News, Research

March 19, 2019

Researchers at UCLA have identified a new stem cell that participates in the repair of the large airways of the lungs, which play a vital role in protecting the body from infectious agents and toxins in the environment. The airways protect the body by producing and...

Signaling Pathway Is ‘Executive Software’ of Airway Stem Cells, Researchers Find

by BEF

CF News, Research

March 19, 2019

Researchers at Duke University Medical Center have found out how mouse basal cells that line airways "decide" to become one of two types of cells that assist in airway-clearing duties. The findings could help provide new therapies for either blocked or thinned airways. "Our work has...

Research

Genzyme and CFFT Announce Collaboration to Discover New CF Drugs

New Clues for Improving Antibiotics for Tolerant Bacteria

Agile Sciences Gets NIH Grant to Study Treatment for Lung Infections

Most Parents Unaware of Medical Research Opportunities for Their Kids

Changes in Lung Stem Cells May Contribute to CF Progression

Battle of the Bugs: Pseudomonas Breaches Cell Wall of Rival Bacteria Without Hurting Itself

New Invasive Diagnostic Procedure Seems to Be No Advantage Over Current Standard Procedure

Bacteria Use Batman-Like Grappling Hooks to ‘Slingshot’ on Surfaces, Researchers Find

Researchers Discover New Airway Stem Cell

Signaling Pathway Is ‘Executive Software’ of Airway Stem Cells, Researchers Find

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