BEF, Author at The Boomer Esiason Foundation

March 19, 2019

Researchers at the University of Iowa's Roy J. and Lucille A. Carver College of Medicine have discovered that in cystic fibrosis (CF) patients, the airway glands are depleted of a specific population of airway stem cells that participate in airway repair following injury. Their results are...

Battle of the Bugs: Pseudomonas Breaches Cell Wall of Rival Bacteria Without Hurting Itself

by BEF

CF News, Research

March 19, 2019

Microbiologists have uncovered a sneaky trick by the bacterium Pseudomonas aeruginosa to oust rivals. It deploys a toxin delivery machine to breach cell walls of competitors without hurting itself. Its means of attack helps it survive in the outside environment and may even help it...

Bacteria Use Batman-Like Grappling Hooks to ‘Slingshot’ on Surfaces, Researchers Find

by BEF

CF News, Research

March 19, 2019

Bacteria use various appendages to move across surfaces prior to forming multicellular bacterial biofilms. Some species display a particularly jerky form of movement known as "twitching" motility, which is made possible by hairlike structures on their surface called type IV pili, or TFP. "TFP act like...

New Invasive Diagnostic Procedure Seems to Be No Advantage Over Current Standard Procedure

by BEF

CF News, Research

March 19, 2019

By Anne Hudsmith, Medical News Today A comparative study published in July 13 issue of JAMA noticed treatment based on a new invasive diagnostic procedure for treating cystic fibrosis in infants that involves obtaining and culturing fluid samples from the lungs, when compared with standard diagnostic...

Researchers Discover New Airway Stem Cell

by BEF

CF News, Research

March 19, 2019

Researchers at UCLA have identified a new stem cell that participates in the repair of the large airways of the lungs, which play a vital role in protecting the body from infectious agents and toxins in the environment. The airways protect the body by producing and...

Signaling Pathway Is ‘Executive Software’ of Airway Stem Cells, Researchers Find

by BEF

CF News, Research

March 19, 2019

Researchers at Duke University Medical Center have found out how mouse basal cells that line airways "decide" to become one of two types of cells that assist in airway-clearing duties. The findings could help provide new therapies for either blocked or thinned airways. "Our work has...

Changing Genetic ‘Red Light’ to Green Holds Promise for Treating Disease

by BEF

CF News, Research

March 19, 2019

In a new study published today in the journal Nature, scientists discovered an entirely new way to change the genetic code. The findings, though early, are significant because they may ultimately help researchers alter the course of devastating genetic disorders, such as cystic fibrosis, muscular...

Rare Diseases Often Caused by Mutations in Essential Genes, Researchers Find

by BEF

CF News, Research

March 19, 2019

Mutations in genes essential to survival are behind so-called orphan diseases, explaining in part why these diseases are rare and often deadly, according to a study appearing in The American Journal of Human Genetics. The new finding contrasts sharply with what is known about mutations in...

CF Bacteria Could Help Combat Other Superbugs, Researchers Find

by BEF

CF News, Research

March 19, 2019

A bacteria which infects people with cystic fibrosis could help combat other antibiotic-resistant microbes, according to a team from Cardiff and Warwick Universities in Great Britain. Continuous use of existing antibiotics means that resistant bacteria are now causing major health problems all over the world. New...

Researchers Identify Genes Linked to Worsening of CF

by BEF

CF News, Research

March 19, 2019

Johns Hopkins Institute for Genetic Medicine researchers working as part of the North American Cystic Fibrosis Consortium have discovered two regions of the genome that affect the severity of cystic fibrosis, a genetic condition that causes scarring throughout the body, affecting most notably the pancreas...

Author: BEF

Changes in Lung Stem Cells May Contribute to CF Progression

Battle of the Bugs: Pseudomonas Breaches Cell Wall of Rival Bacteria Without Hurting Itself

Bacteria Use Batman-Like Grappling Hooks to ‘Slingshot’ on Surfaces, Researchers Find

New Invasive Diagnostic Procedure Seems to Be No Advantage Over Current Standard Procedure

Researchers Discover New Airway Stem Cell

Signaling Pathway Is ‘Executive Software’ of Airway Stem Cells, Researchers Find

Changing Genetic ‘Red Light’ to Green Holds Promise for Treating Disease

Rare Diseases Often Caused by Mutations in Essential Genes, Researchers Find

CF Bacteria Could Help Combat Other Superbugs, Researchers Find

Researchers Identify Genes Linked to Worsening of CF

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